| 大青叶化学成分研究 |
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| 引用本文： | 阮金兰,邹建华,蔡亚玲. 大青叶化学成分研究[J]. 中国中药杂志, 2005, 30(19): 1525-1526 |
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| 作者姓名： | 阮金兰 邹建华 蔡亚玲 |
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| 作者单位： | 1. 华中科技大学,同济药学院,湖北,武汉,430030
2. 中国医学科学院,中国协和医科大学,药物研究所,北京,100050 |
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| 基金项目： | 中国科学院资助项目，湖北省自然科学基金 |
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| 摘 要： | 目的:研究大青叶乙醇总提取物中的化学成分。方法:应用各种柱色谱方法对其提取物进行化学成分分离,并应用化学方法和现代波谱分析方法鉴定所分离得到的化学成分。结果:从大青叶乙醇总提取物中分离得到3个化合物,经鉴定为吲哚类化合物靛玉红(indirubin)、喹唑酮类化合物色胺酮(tryptanthrin)及焦谷氨酸(L-py-roglutamic acid)。结论:焦谷氨酸为首次从菘蓝属植物中分离得到,色胺酮系从该植物叶中首次分离得到。
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| 关 键 词： | 大青叶 化学成分 靛玉红 色胺酮 焦谷氨酸 |
| 文章编号： | 1001-5302（2005）19-1525-02 |
| 收稿时间： | 2004-09-05 |
| 修稿时间： | 2004-09-05 |
Studies on chemical constituents in leaf of Isatis indigotica |
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| RUAN Jin-lan;ZOU Jian-hua;CAI Ya-ling. Studies on chemical constituents in leaf of Isatis indigotica[J]. China Journal of Chinese Materia Medica, 2005, 30(19): 1525-1526 |
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| Authors: | RUAN Jin-lan ZOU Jian-hua CAI Ya-ling |
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| Affiliation: | College of Pharmacy, Tongji Medical Center of Huazhong University of Science and Technology, Wuhan 430030, China. jinlan5952@hotmail.com |
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| Abstract: | Objective: To study the chemical constituents of the leaf of Isatis indigotica.Method: Chromatography and spectral analysis were respectively used to isolate and identify the constituents.Result: Three compounds were isolated from the ethanol extracts of the leaf of I.indigotica,and identified as indirubin,tryptanthrin and L-pyroglutamic acid.Conclusion: L-pyroglutamic acid was isolated from the genus for the first time,and tryptanthrin was isolated from the leaf of this plant for the first time. |
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| Keywords: | Isatis indigotica chemical constituents indirubin tryptanthrin L-pyroglutamic acid |
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