Nodular sclerosing Hodgkin's disease and large cell lymphoma. Immunophenotypic characterization of a composite case |
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| Authors: | M. Paulli R. Rosso S. Kindl E. Boveri M. Sirchi A. De Medici R. Invernizzi U. Magrini |
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| Affiliation: | (1) Department of Anatomical Pathology, University of Pavia, I.R.C.C.S. Policlinico S. Matteo, Pavia, Italy;(2) Department of Surgery, University of Pavia, I.R.C.C.S. Policlinico S. Matteo, Pavia, Italy;(3) Department of Internal Medicine, University of Pavia, I.R.C.C.S. Policlinico S. Matteo, Pavia, Italy;(4) Department of Human Pathology, Anatomical Pathology Section, University of Pavia, Via Forlanini, 14, I-27100 Pavia, Italy |
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| Abstract: | Summary Composite lymphomas have rarely been reported in Hodgkin's disease (HD), except in the lymphocyte predominance sub-type, and immunohistochemical investigations have been performed in only few cases. We describe the histological and immunophenotypical findings in a case of composite nodular sclerosing HD and high-grade, large cell non-Hodgkin's lymphoma (NHL). In our case HD and NHL cells displayed striking morphological and immunophenotypical divergence, suggesting a lack of correlation between the two neoplasms. |
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| Keywords: | Composite lymphoma Hodgkin's disease Non-Hodgkin's lymphoma Immunohistochemistry |
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