我院105例药品不良反应报告分析

目的了解我院药品不良反应（ADR）发生的特点,为临床合理用药提供参考。方法对我院2007～2008年收集的105例ADR报告分别从患者年龄、性别、给药途径、引起ADR的药品种类、涉及器官或系统以及临床表现等方面进行统计分析。结果105例ADR涉及的药品有47种,其中抗感染药物所致ADR居首位（占35.24%）,其次是中药制剂（占25.71%）;给药途径以静脉给药引发ADR为主（占74.29%）;ADR临床表现以皮肤粘膜损害最常见（占24.76%）。结论应加强ADR的监测,合理使用药物,避免ADR的重复发生。

Analysis of 105 ADR Cases Report in Our Hospital

Objective To understand the characteristics of ADRs in our hospital to provide a reference for clinic rational drug use. Methods A total of 105 ADR cases collected from 2007 to 2008 in our hospital were statistically analyzed in respect of patients＇ age and sex,route of administration,drug categories inducing ADR,the organs or system involved and the clinical manifestations etc. Results A total of 47 drugs were involved in the 105 ADR,mainly anti-infective drugs （35.24%）,followed by Chinese medicines （25.71%）. Intravenous drug delivery was the main way（74.29%）; mucocutaneous damage were the most common （24.76%）. Conclusion ADR monitoring should be strengthened to the rational use of drugs so as to avoid duplication of ADR occurred.