宫颈球囊、欣普贝生及催产素引产对母婴结局的影响

目的：探讨宫颈球囊、欣普贝生、催产素三种引产方法对母婴结局的影响。方法回顾性分析2014年1月至2016年1月在我院分娩的720例有引产指征的孕妇的临床资料，根据引产方式的不同分为三组，A组进行球囊引产（300例），B组使用普贝生引产（200例），C组使用催产素引产(220例)，对三组产妇的分娩方式、引产成功率、产程时间、围生儿结局等进行比较。结果 A、B、C三组孕妇的引产总有效率分别为85.00%、92.00%、75.00%， C组孕妇的引产总有效率明显低于A组和B组，差异均有统计学意义(P<0.05)；C组孕妇的剖宫产率为37.27%，明显高于A组和B组，差异均有统计学意义(P<0.05)；A、B二组孕妇的用药到临产时间分别为(11.14±5.33) h、(10.21±5.61) h，均明显短于C组的(28.64±10.64) h，差异均有统计学意义(P<0.05)；A、B、C三组新生儿出生5 min的Apgar评分分别为（9.57±0.60）分、(9.55±0.62)分、(9.52±0.58)分，三组比较差异无统计学意义(P>0.05)；三组产妇的产褥感染、羊水粪染、宫颈裂伤、新生儿窒息及宫内感染发生率比较差异均无统计学意义(P>0.05)。结论三种引产方式均能促进宫颈成熟，但比起单一催产素引产，欣普贝生和宫颈球囊的引产效果更好，宫颈球囊的引产成功率略低于欣普贝生，但是缩短临产时间的效果最为显著，同时引产安全性更好。

Effect of cervical balloon,Propess pessary and oxytocin on pregnancy outcome

Objective To investigate the effect of cervical balloon, Propess pessary and oxytocin on maternal and neonatal outcomes. Methods The clinical data of 720 cases of pregnant women with induction indications in our hospital from January 2014 to January 2016 were retrospectively analyzed. These patients were divided into the three groups according to the different method of labor induction: cervical balloon used to induce labor in the group A (n=300); Propess pessary used to induce labor in the group B (n=200); oxytocin used to induce labor in the group C (n=220). The maternal mode of delivery, success rate of labor induction, time of birth process, perinatal outcomes in the three groups were compared. Results The total effective rates of labor incubation in group A, B and C were 85.00%, 92.00%, 75.00%, respectively, and the rate in the group C was significantly lower than that in the group A and B (P<0.05). The rate of cesarean section in the group C was 37.27%, which was significantly higher than that in group A and B (P<0.05). The time from drug-using to labor in the group A and B were respectively (11.14 ± 5.33) h and (10.21 ± 5.61) h, which were significantly shorter than (28.64±10.64) h in the group C (P<0.05). The 5-minute Apgar scores of group A, B and C were respectively (9.57±0.60), (9.55±0.62) and (9.52±0.58), and there was no significant difference between the three groups (P>0.05). There were no significant differences in the incidence of puerperal infection, meco-nium-stained amniotic fluid, cervical laceration, neonatal asphyxia and intrauterine infection among the three groups (P>0.05). Conclusion These three methods of labor induction can promote cervical ripening, but compared to induc-ing labor with single oxytocic hormone, cervical balloon and Propess pessary have better effects. The effective rate of in-ducing labor of cervical balloon is slightly lower than that of Propess pessary, but the effect of shortening the labor time is the most significant and the safety of induction of labor is better.