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愈伤灵膏的抗炎镇痛作用
引用本文:李艳春,马恩龙,甘乐凌,王敏伟. 愈伤灵膏的抗炎镇痛作用[J]. 沈阳药科大学学报, 2004, 21(6): 454-457
作者姓名:李艳春  马恩龙  甘乐凌  王敏伟
作者单位:沈阳药科大学,药学院,辽宁,沈阳,110016
基金项目:辽宁省科学技术计划项目 (982 2 6 0 0 3)
摘    要:目的研究愈伤灵膏的抗炎镇痛作用。方法采用血管通透性实验、小鼠耳肿胀实验、大鼠角叉菜胶性足跖肿胀实验、小鼠光热法及醋酸所致小鼠扭体反应等炎症、疼痛模型考察愈伤灵膏的抗炎镇痛作用。结果愈伤灵膏可明显抑制烫伤部位毛细血管通透性 ;对角叉菜胶致大鼠足肿胀和二甲苯致小鼠耳肿胀有明显的抑制作用 ;对光热致小鼠足部疼痛、醋酸致小鼠扭体均有明显的镇痛效果。结论愈伤灵膏具有明显的抗炎、镇痛药效

关 键 词:镇痛  抗炎  愈伤灵膏
文章编号:1006-2858(2004)06-0454-04
修稿时间:2003-11-18

Anti-inflammatory and analgesic effect of the Yushangling Ointment
LI Yan-chun,MA En-long,GAN Le-ling,WANG Min-wei. Anti-inflammatory and analgesic effect of the Yushangling Ointment[J]. Journal of Shenyang Pharmaceutical University, 2004, 21(6): 454-457
Authors:LI Yan-chun  MA En-long  GAN Le-ling  WANG Min-wei
Abstract:Objective To study anti-inflammatory and analgesic effect of the Yushangling Ointment.Methods Different pain and inflammatory models were made to investigate the anti-inflammatory and analgesic effects of the Yushangling Ointment.Results The results of the anti-inflammatory experiments showed that ear edema resulted from dimethyl benzene and paw edema induced by carragheenin were significantly inhibited by the Yushangling Ointment; permeability of micro-vessels of post-burned wound in rats and mice was greatly decreased.And the Yushangling Ointment also produced obvious analgesic effects on the pain model of body-twisting caused by acetic stimulus in mice and light-heat stimulation in mice.Conclusion The Yushangling Ointment has significant anti-inflammatory and analgesic effect.
Keywords:analgesic effect  anti-inflammatory effect  Yushangling Ointment
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