冠心病合并2型糖尿病患者冠状动脉内支架术后的远期随访

Objective To observe the ang/ographic characteristics and the long-term clinical outcomes following coronary stenting in non-diabetic (non-DM) and type 2 diabetic (DM) patients with coronary artery disease. Methods This cohort study enrolled 1172 consecutive patients with coronary heart disease underwent elective coronary stenting (249 type 2 DM and 923 non-DM). The angiographic characteristics and the long-term clinical follow-up results were compared between non-DM and DM patients. Results The follow-up period was (39.2±6.4) months (6-83 months), follow-up rate was 90.3% in DM and 91.0% in uon-DM group (P＞0.05). Compared with non-diabetic patients, there were significantly higher incidences of 2-veasel (P = 0.029) and 3-vessel (P = 0.013) diseases of coronary artery, severe stenosis lesion(P =0.012), chronic total obstructive lesion(P =0.044) and long lesion(P =0.001), in-stent restenosis (ISR,P =0.000) and revascularization(P =0.000) and MACE(P =0.000) in DM patients. COX multiple factorial analysis showed that DM is independent risk factor for ISR (P = 0.000), revascularization(P =0.001) and MACE(P=0.003). Conclusions CHD patients with type 2 DM are associated with multi- and more severe vessel lesions. Type 2 DM is also an independent risk factor for increased ISR, revascularization and MACE post stenting.

Angiographic characteristics and long term clinical outcomes post coronary stenting in non-dlabetic and type 2 diabetic patients with coronary artery disease