| HBV感染的HBcAb动力学观察 |
| |
| 引用本文： | 刘树贤,刘茂松,黄朝南,李荣芝,徐文兰,牟振云,刘增平,王俊增. HBV感染的HBcAb动力学观察[J]. 河北医科大学学报, 1986, 0(2) |
| |
| 作者姓名： | 刘树贤 刘茂松 黄朝南 李荣芝 徐文兰 牟振云 刘增平 王俊增 |
| |
| 摘 要： | HBcAb在HBV感染个体中的出现和持续状态已被清楚地证明,并把它视为HBV感染的一个血清学重要指标。为了进一步探讨它在临床学和流行病学上的意义,本文研究了159例正常人的HBcAb。经两年的追踪观察,发现HBcAb检出率高于乙型肝炎的其它血清学指标,并发现HBcAb滴度与HBsAg滴度间存在着正相关,同时有按滴度变动的依存关系,即呈对数曲线形式(R~2=0.96033)。此结果为今后检测HBcAb与HBsAg指标的数量分析提出了参考依据。
|
| 关 键 词： | 乙型肝炎病毒 免疫学 乙型肝炎核心抗体 乙型肝炎表面抗原 发生 |
KINETIC OBSERVATION OF ANTIBODY AGAINST HEPATITIS B CORE ANTIGEN IN HEPATITIS B VIRUS INFECTION |
| |
| Abstract: | It has clearly been proven that antibody against hepatitis B core antigen(anti-HBc) is present and persistent in individual with hepatitis B virus(HBV) infection. Anti-HBc war regarded as an important serologic marker of HBV infection. To inquire further into its clinical and epidemiologic significance, anti-HBc in 159 normal population was studied.Two years follow-up observation showed that detecting rate of the anti-HBc was higher than that of other serologic markers of hepatitis B. A positive correlation and interdependent relationship existed between anti-HBc titer and HBsAg titer in quantity, i. e., the form of logarithic curve(R~2=0.9603). The results will provide reference evidence of quantitative measurement analysis for detecting anti-HBc and HBsAg indexes in future. |
| |
| Keywords: | hepatitis B virus immunology hepatitis B core antibodies hepatitis B surface antigens occurence |
|
|
