| 茱萸颗粒对大鼠心肌细胞抗柯萨奇病毒感染的实验研究 |
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| 引用本文： | 王宁皎 朱萱萱 吴跃军 彭娟 李七一. 茱萸颗粒对大鼠心肌细胞抗柯萨奇病毒感染的实验研究[J]. 南京中医药大学学报, 2005, 21(1): 31-33 |
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| 作者姓名： | 王宁皎 朱萱萱 吴跃军 彭娟 李七一 |
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| 作者单位： | 南京中医药大学附属医院,江苏,南京,210029;南京中医药大学附属医院,江苏,南京,210029;南京中医药大学附属医院,江苏,南京,210029;南京中医药大学附属医院,江苏,南京,210029;南京中医药大学附属医院,江苏,南京,210029 |
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| 基金项目： | 江苏省科委社会发展项目资助 (BJ980 3 8) |
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| 摘 要： | 目的 观察茱萸颗粒对大鼠心肌细胞抗CVB3病毒感染的作用。方法 用CVB3病毒感染大鼠心肌细胞 ,观察正常心肌对照组、病毒感染组、茱萸颗粒给药组心肌细胞病理变化和心肌酶谱变化。结果 茱萸颗粒可明显降低CVB3病毒感染后心肌细胞的病理改变和心肌细胞酶的释放 ,茱萸颗粒浓度 4 .0mg/mL的给药组与病毒对照组有非常显著差别。结论 茱萸颗粒具有较强的保护心肌细胞和助心肌细胞抗CVB3病毒感染的作用
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| 关 键 词： | 茱萸颗粒 心肌细胞 柯萨奇病毒 |
| 文章编号： | 1000-5005(2005)01-0031-03 |
| 修稿时间： | 2004-10-21 |
Experimental Study on Effect of Zhuyu Granule on Rat Myocardial Cell in Fighting against CVB3 Virus Infection |
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| WANG Ning-jiao,ZHU Xuan-xuan,WU Yao-jun,PENG Ju-an,LI Qi-yi. Experimental Study on Effect of Zhuyu Granule on Rat Myocardial Cell in Fighting against CVB3 Virus Infection[J]. Journal of Nanjing University of Traditional Chinese Medicine(Natural Science), 2005, 21(1): 31-33 |
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| Authors: | WANG Ning-jiao ZHU Xuan-xuan WU Yao-jun PENG Ju-an LI Qi-yi |
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| Abstract: | OBJECTIVE To observe the effect of Zhuyu Granule on the rat myocardial cell in fighting against CVB3 virus infection. METHOD Myocardial cells of rats infected by CVB3 virus were used to observe the pathological changes and myocardium zymogram changes. RESULT Zhuyu Granule could markedly reduce the pathological changes of the myocardial cells after infection and the release of myocardial cell enzyme. The result obtained in the group treated with Zhuyu Granule at the concentration of 4.0 mg/mL is significantly different from the virus control group. CONCLUSION Zhuyu Granule has strong effect of protecting myocardium and preventing CVB3 virus infection. |
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| Keywords: | Zhuyu Granule myocardial cell CVB3 virus |
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