肝豆状核变性的颅脑CT诊断(附39例报告)

目的分析肝豆状核变性的颅脑CT征象,进一步提高对W ilson病的认识及诊断的正确率。方法全部病例均行脑CT扫描,回顾性分析其CT征象及临床表现。结果31例壳核出现对称性带状或弓状向外新月形低密度区,形如“八字”或“展翅蝴蝶”样;3例尾状核头见卵圆形低密度区;4例丘脑见对称性卵圆形低密度区;1例脑实质内未见异常密度但有脑萎缩表现。全部病例均有不同程度的脑沟裂增宽等脑萎缩表现。结论肝豆状核变性颅脑CT最多见征象是脑萎缩与基底节低密度灶,特别是双侧豆状核区对称性低密度灶最具有特征性。

CT Diagnosis of the Hepatolenticular Degeneration(A Report of 39 Cases)

Objective To improve knowledge of the Wilson's disease by analysing its CT findings of the head.Methods CT scans were performed in all cases,CT findings of head were analysed retrospectively.Results CT findings were mainly brain atrophy and the low density of basal ganglia.31 cases had symmetrical ribbon-like or crescent low density in the lentiform nuclei,three had oval low density inthe caudate nucleus,four had symmetrical oval low density in the thalamus,one was normal but atrophy.All cases had brain atrophy.Conclusion The most common CT findings in hepatolenticular degeneration patients are mainly brain atrophy and low density of the basal ganglia,especially the symmetrical low density of the lentiform nuclei is characteristic of Wilson disease on CT.