Ahmed FP-7青光眼引流阀治疗难治性青光眼的18个月效果

目的 评估Ahmed FP-7青光眼阀植入治疗难治性青光眼的效果。设计 回顾性病例系列。研究对象 哈尔滨医科大学附属第二医院难治性青光眼患者45例46眼。方法 对以上患者行Ahmed FP-7青光眼阀植入，术后平均随访（10.7±7.3）个月。不用降眼压药眼压≤21 mm Hg定义为成功。主要指标 眼压、视力、手术后并发症。结果 术后18个月成功率为74.1 %；术前平均眼压（45.8±12.1）mm Hg，术后18个月为（17.6±5.3）mm Hg （P<0 .001）。视力提高 9眼，无改变35眼。手术并发症包括引流盘纤维包裹9眼（19.6%）、脉络膜脱离6眼（13.0%）、前房出血5眼（10.9%）、引流管暴露2眼（4.3%）。结论 18个月的随访显示，Ahmed FP-7青光眼阀植入术可控制3/4的难治性青光眼患者的眼压。（眼科，2013，22：253-256）

The 18 months results of Ahmed FP-7 glaucoma valve for treatment of refractory glaucoma

Objective To evaluate the efficacy of Ahmed FP-7 implantation in refractory glaucoma. Design Retrospective case series. Participants 45 cases (46 eyes) of refractory glaucoma in the 2nd Affiliated Hospital of Harbin Medical University. Methods Ahmed FP-7 glaucoma valve implantations were performed in all patients, and mean follow-up was 10.7±7.3 months. Main Outcome Measures Intraocular pressure (IOP), visual acuity, and postoperative complications. Results The cumulative probability of success (IOP≤ 21 mm Hg without antiglaucoma medications) was 79.8% and 74.1 % at 12 and 18 months, respectively. IOP was reduced from a mean of 45.8±12.1 mm Hg to17.3±5.5 mm Hg at 12 months and 17.6±5.3 mm Hg at 18 months (P<0.001). Visual acuity improved in 9 eyes, and no change in 35 eyes. The major postoperative complications including filtering bleb fiber encapsulation (19.6%), choroidal detachment (13.0%), hyphema (10.9%), drainage tube exposure (4.3%). Conclusion Ahmed FP-7 implantations in refractory glaucoma can control IOP in 75% of patients during 18 months follow-up. (Ophthalmol CHN, 2013, 22: 253-256)