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Polymorphisms in the serotonin transporter protein (SERT) gene in patients with pulmonary arterial hypertension |
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| Authors: | Baloira Adolfo Núñez Marta Cifrian José Vilariño Carlos Ojeda María Valverde Diana |
| Affiliation: | Servicio de Neumología, Complexo Hospitalario de Pontevedra, Spain. adolfo.baloira.villar@sergas.es |
| Abstract: | Serotonin is a potent vasoconstrictor and pulmonary vascular growth factor whose concentration is increased in patients with pulmonary arterial hypertension (PAH). Its functions are mediated in part by the serotonin transporter protein (SERT) whose gene can have two allelic forms, both long (L) and short (S). The first was associated with greater function. |
| Keywords: | Serotonina Hipertensión arterial pulmonar Proteína transportadora de serotonina (SERT) Polimorfismos |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |