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Effects of ubiquinone-10 on energy metabolism and lipid peroxidation in rats with myocardial ischemia
Authors:Krylov V N  Luk'yanova L D  Koryagin A S  Yastrebova E V
Affiliation:(1) Department of Human and Animal Physiology and Biochemistry, N. I. Lobachevskii Nizhny Novgorod State Medical University, Russia;(2) Laboratory of Bioenergetics, Institute of Pharmacology, Russian Academy of Medical Sciences, Russia
Abstract:Preventive and therapeutic intraventricular administration of ubiquinone-10 to male rats with epinephrine-induced myocarditis increased the rate of oxidative phosphorylation, elevated the content of ATP, and inhibited lipid peroxidation in ischemic myocardium. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 7, pp. 35–38, July, 2000
Keywords:myocardial ischemia    oxidative phosphorylation    lipid peroxidation    ubiquinone-10
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