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Primary Renal Malignant Fibrous Histiocytoma Four-Case Report and Review of the Literature
引用本文:XinYao BaocunSun WenluLi HuaChen ZhaoxiangYe CuiWang. Primary Renal Malignant Fibrous Histiocytoma Four-Case Report and Review of the Literature[J]. 中国肿瘤临床(英文版), 2004, 1(4): 241-249. DOI: 10.1007/BF02739808
作者姓名:XinYao BaocunSun WenluLi HuaChen ZhaoxiangYe CuiWang
作者单位:[1]DepartmentofUrologicCancerHospital&InstituteMedicalUniversity,TianjinChina.Oncology,ofTianjin [2]DepartmentofPathology,CancerHospital&InstituteofTianjinMedicalUniversity,Tianjin300060,China [3]DepartmentofRadiology,CancerHospital&InstituteofTianjinMedicalUniversity,Tianjin300060,China
摘    要:OBJECTIVE To evaluate the diagnosis and treatment for primary renal malignant fibrous histiocytoma, a rare tumor arising from the kidney.METHODS The clinical and pathological data from 4 cases of malignant fibrous histiocytoma of the kidney detected in our hospital are described.One case of special interest involved a giant cell subtype, the first to be reported in the oncology literature. The clinicopathologic features and prognostic factors of this tumor were analysed and summarized after reviewing 55 documented cases in the English and Chinese literature.RESULTS A palpable mass (71.2%), emaciation (54.2%) and pain (54,2%) were common manifestations in renal MFH, Of all the cases, 51 were identified as a storiform-pleomorphic subtype by pathologists. Inconsideration of all the prognosis related factors, the residual tumor and high TNM stage predicted a shortened survival duration, but the symptom of a fever served as a better prognostic factor.CONCLUSION Malignant fibrous histiocytoma which arises from the kidney is a rare pathologic type, and possesses a high tendency towards local recurrence and distant metastasis. Despite the poor prognosis, early detection and radical surgery can prolong survival in selected cases.

关 键 词:初级 肾脏 恶性纤维组织瘤 病例报告 TNM
收稿时间:2004-05-07
修稿时间:2004-06-28

Primary renal malignant fibrous histiocytoma four-case report and review of the literature
Xin Yao, Baocun Sun, Wenlu Li, Hua Chen, Zhaoxiang Ye and Cui Wang. Primary renal malignant fibrous histiocytoma four-case report and review of the literature[J]. Chinese Journal of Clinical Oncology, 2004, 1(4): 241-249. DOI: 10.1007/BF02739808
Authors:Xin Yao   Baocun Sun   Wenlu Li   Hua Chen   Zhaoxiang Ye  Cui Wang
Affiliation:(1) Department of Urologic Oncology, Cancer Hospital & Institute of Tianjin Medical University, 300060 Tianjin, China;(2) Department of Pathology, Cancer Hospital & Institute of Tianjin Medical University, 300060 Tianjin, China;(3) Department of Radiology, Cancer Hospital & Institute of Tianjin Medical University, 300060 Tianjin, China
Abstract:Objective To evaluate the diagnosis and treatment for primary renal malignant fibrous histiocytoma, a rare tumor arising from the kidney. Methods The clinical and pathological data from 4 cases of malignant fibrous histiocytoma of the kidney detected in our hospital are described. One case of special interest involved a giant cell subtype, the first to be reported in the oncology literature. The clinicopathologic features and prognostic factors of this tumor were analysed and summarized after reviewing 55 documented cases in the English and Chinese literature. Results A palpable mass (71.2%), emaciation (54.2%) and pain (54.2%) were common manifestations in renal MFH. Of all the cases, 51 were identified as a storiform-pleomorphic subtype by pathologists. In consideration of all the prognosis related factors, the residual tumor and high TNM stage predicted a shortened survival duration, but the symptom of a fever served as a better prognostic factor. Conclusion Malignant fibrous histiocytoma which arises from the kidney is a rare pathologic type, and possesses a high tendency towards local recurrence and distant metastasis. Despite the poor prognosis, early detection and radical surgery can prolong survival in selected cases.
Keywords:Kidney  malignant  fibrous histiocytoma
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