Association of Zollinger-Ellison Syndrome with Pancreatitis |
| |
Authors: | Gyõrgy Baffy James M. Boyle |
| |
Affiliation: | (1) Department of Medicine, Saint Luke's Medical Center, Cleveland, Ohio |
| |
Abstract: | In a retrospective analysis, five cases of Zollinger-Ellison syndrome were found in a typical urban inner-city teaching hospital. Chronic alcohol abuse and heavy smoking characterized these patients, and four of them also had pancreatitis, suggesting an association of gastrin-producing tumors and pancreatic inflammation. Ductal obstruction by neuroendocrine tumors has been reported to cause pancreatitis in a few cases. In this analysis, however, a nonobstructive gastrinoma was the surgical diagnosis in three patients, and it was suggested by imaging studies in the two other cases. The potential other pathomechanisms for a dual cause–effect relationship of gastrinoma and pancreatitis are discussed. |
| |
Keywords: | pancreatitis Zollinger-Ellison syndrome gastrinoma |
本文献已被 PubMed SpringerLink 等数据库收录! |
|