| 原络通经针法配合药物治疗对轻度认知功能障碍患者事件相关电位P300的影响 |
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| 引用本文： | 孙远征,孙兴华,张淼.原络通经针法配合药物治疗对轻度认知功能障碍患者事件相关电位P300的影响[J].上海针灸杂志,2012,31(1):12-14. |
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| 作者姓名： | 孙远征 孙兴华 张淼 |
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| 作者单位： | 1. 黑龙江中医药大学附属第二医院,哈尔滨,150001
2. 黑龙江中医药大学,哈尔滨,150040 |
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| 基金项目： | 黑龙江省教育厅2009年度科学技术研究项目 |
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| 摘 要： | 目的观察原络通经针法配合药物治疗对轻度认知功能障碍患者事件相关电位P300的影响。方法将40例轻度认知功能障碍患者随机分为治疗组和对照组,每组20例。治疗组采用原络通经针法配合药物治疗,对照组采用单纯药物治疗。采用肌电-诱发电位仪听觉odball程序由同一操作者于治疗前后各检查1次,并由专业人员于治疗前后进行简易智能量表评测。结果治疗组总有效率为90.0%,对照组为75.0%,两组比较差异具有统计学意义(P<0.05)。两组治疗后简易智能量表评分均较同组治疗前有明显提高(P<0.01,P<0.05);治疗组治疗后简易智能量表评分与对照组比较,差异具有统计学意义(P<0.05)。两组治疗后N2、P3潜伏期较同组治疗前明显缩短(P<0.01,P<0.05),波幅明显增高(P<0.01,P<0.05);治疗组治疗后N2、P3潜伏期与波幅与对照组比较,差异均具有统计学意义(P<0.05)。结论原络通经针法配合药物治疗可以改善轻度认知功能障碍患者认知功能。
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| 关 键 词： | 针刺疗法 轻度认知功能障碍 事件相关电位P300 |
Effect of Yuan-primary and Luo-connecting Needling Method plus Medication on P300 in Patients with Mild CognitiveDisorder |
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| SUN Yuan-zheng
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SUNXing-hua
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ZHANG Miao.Effect of Yuan-primary and Luo-connecting Needling Method plus Medication on P300 in Patients with Mild CognitiveDisorder[J].Shanghai Journal of Acupuncture and Moxibustion,2012,31(1):12-14. |
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| Authors: | SUN Yuan-zheng SUNXing-hua ZHANG Miao |
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| Institution: | 1 .No.2 Hospital Affiliated to Heilonyjiang University of Traditional Chinese Medicine,Harbin 150001,China; 2.Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China) |
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| Abstract: | Objective To observe the influence of Yuan-primary and Luo-connecting needling method plus medication on the event-related potential 300 （P300） in patients with mild cognitive disorder. Method Forty patients with mild cognitive disorder were randomized into a treatment group and a control group, 20 in each. The treatment group was managed by Yuan-primary and Luo-connecting needling method plus medication, and the control group was managed by medication only. The evoked potential （EP） instrument with auditory oddball paradigm and the Modified Intelligence Scale （MIS） were adopted for evaluation before and after treatment by professionals. Result The total effective rate was 90.0% in the treatment group versus 75.0% in the control group, and the difference was statistically significant （P〈0.05）. The MIS score had marked improvement in both groups after treatment （P〈 0.01 ,P〈 0.05）. After treatment, the MIS score in the treatment group was significantly better than that in the control group （P〈 0.05）. The N2 and P3 latencies were obviously shortened in both groups after treatment （P〈0.01,P〈0.05）, and the amplitude was also significantly increased （P〈0.01,P〈0.05）. After treatment, N2 and P3 latencies and amplitude in the treatment group were markedly different from that in the control group （P〈0.05）. Conclusion Yuan-primary and Luo-connecting needling method plus medication can significantly improve the cognitive function of the patients with mild cognitive disorder. |
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| Keywords: | Acupuncture therapy Mild cognitive disorder Event-related potential 300 |
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