不同剂量硝酸甘油治疗急性心肌梗死效果比较

目的　观察不同剂量硝酸甘油治疗急性心肌梗死 (AMI)的效果。方法　观察 2所医院共 174例男性AMI患者 ,分别应用大剂量和小剂量硝酸甘油 ,根据胸痛缓解率、三大并发症发生率和病死率等组间比较判断 2种治疗方法的优缺点。结果　两组硝酸甘油应用总剂量和应用时间有显著性差异 ;两组胸痛缓解率、低血压发生率、三大并发症发生率和病死率均无显著性差异。结论　 2种治疗方法均可使 85 %的AMI患者胸痛症状缓解 ,但是大剂量并不比小剂量有特别优越之处。

Effect contrast of different dosages of nitroglycerin on acute myocardial infarction

Objective It is to study curative effect of different dosage of nitroglycerin on acute myocardial infarction (AMI).Methods 174 male AMI inpatients in two hospitals were respectively administrated with large and small dosage nitroglycerin. The merit and shortcoming of two dosages were compared according to the release rate of pectoralgia, occurrence rate of three main complications and case fatality rate. Results Total dosages and applying time of nitroglycerin between two groups were significant difference. No significant difference was found between the release rates of pectoralgia, occurrence rates of three main complications and case fatality rates in two groups. Conclusion Both methods can relieve pectoralgia in 85 percent patients of AMI, and large dosage is not superior to small dosage of nitroglycerin.