Comparison of the blood level of endogenous paramagnetics in health and pathology using proton magnetic relaxation |
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| Authors: | M G Gangardt N F Karyakina A S Pavlov E A Papish |
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| Institution: | (1) Department of Clinical Radiology, Russian Postgraduate Medical Academy, Moscow |
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| Abstract: | An experimental study is made of the longitudinal proton relaxation timeT
1 in human serum in health and pathology as a function of the protein concentration using partially lyophilized samples. A
comparison of the results with those obtained with modeled aqueous protein solutions and extrapolation of the dependences
to the zero concentration demonstrate that the concentration of paramagnetic admixtures is the same in groups of healthy subjects
and patients with malignant neoplasms who have reliably differentT
1 values in native samples. There is no difference in the longitudinal proton relaxation time of the nonaqueous component of
the serum between these groups.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N
o
11, pp. 557–560, November, 1995 |
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| Keywords: | NMR relaxation blood serum pathology paramagnetic centers mass ratio |
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