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子宫颈癌治疗性疫苗研究进展
引用本文:徐道华,夏永鹏,邱宗荫.子宫颈癌治疗性疫苗研究进展[J].免疫学杂志,2004,20(Z1):46-49.
作者姓名:徐道华  夏永鹏  邱宗荫
作者单位:1. 重庆医科大学药学系,重庆,400016;重庆市药品食品监督管理局,重庆,400016
2. 重庆市药品食品监督管理局,重庆,400016
3. 重庆医科大学药学系,重庆,400016
摘    要:子宫颈癌为妇女最常见的恶性肿瘤之一,其与人乳头瘤病毒(HPV)密切相关.HPV早期基因E6、E7的持续表达是维持癌细胞转化状态所必须的.因此,E6、E7可作为宫颈癌治疗的靶点.目前,针对HPV E66、E7的治疗性疫苗已取得了较大进展.本文就近年来子宫颈癌治疗性疫苗的最新进展进行了综述.

关 键 词:子宫颈癌  人乳头瘤病毒  治疗性疫苗
文章编号:1000-8861(2004)03(S)-0046-04
修稿时间:2004年3月31日

Advance of the therapeutic vaccine against cervical cancer
XU Dao-hua.Advance of the therapeutic vaccine against cervical cancer[J].Immunological Journal,2004,20(Z1):46-49.
Authors:XU Dao-hua
Abstract:Cervical cancer, one of the most common cancers in woman, is closely associated with human papilloma virus (HPV) infection. The lasting expressions of HPV gene E6 and E7 are required for maintaining the transforming behavior of cervical carcinoma cell. Therefore, E6 and E7 are popular targets for immunotherapy of cervical cancer. Great advance in therapeutic vaccine for HPV gene E6 and E7 has been achieved in recent years, and in the article the advance of the therapeutic vaccine against cervical cancer is reviewed.
Keywords:rvical cancer  Human papilloma virus (HPV)  Therapeutic vaccine
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