| Nogo-A与缺血后适应脑保护作用的研究进展 |
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| 引用本文： | 钱芳. Nogo-A与缺血后适应脑保护作用的研究进展[J]. 医学综述, 2012, 18(15): 2358-2360 |
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| 作者姓名： | 钱芳 |
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| 作者单位： | 昆明医学院第二附属医院神经内科,昆明,650101 |
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| 基金项目： | 云南省科技厅-昆明医学院联合专项基金，硕士创新基金 |
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| 摘 要： | 轴索过度生长抑制因子A(Nogo-A)是近年来人们在中枢神经系统髓磷脂中研究发现的一种抑制轴突生长的蛋白,对神经细胞再生有显著的抑制作用。缺血后适应是近年来发现的一种新的干预措施,作为缺氧耐受现象的一种,可以显著地减轻缺血/再灌注损伤。现就Ngoo-A与缺血后适应脑保护的研究进行综述,探讨两者与神经损伤修复的关系。
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| 关 键 词： | 轴索过度生长抑制因子A 缺血后适应 神经修复 |
Research Progress on Cerebral Protective Effect of Ischemic Postconditioning and Nogo-A |
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| QIAN Fang. Research Progress on Cerebral Protective Effect of Ischemic Postconditioning and Nogo-A[J]. Medical Recapitulate, 2012, 18(15): 2358-2360 |
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| Authors: | QIAN Fang |
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| Affiliation: | .(Department of Neurology,Kunming Medical College Second Affiliated Hospital,Kunming 650101,China) |
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| Abstract: | Neurite outgrowth inhibitor-A(Nogo-A)is one type of protein which inhibit the growth of axon discovered in the study of the central nervous system myelin in recent years,which obviously restrains regeneration of nerve cells.As a kind of phenomenons of hypoxia tolerance,ischemic postconditioning may lessen ischemia/reperfusion injury remarkably.Here is to make a review on Nogo-A and ischemic postconditioning in the study of brain protection to explore the relationship between them and nerve repair. |
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| Keywords: | Neurite outgrowth inhibitor-A Ischemic postconditioning Nerve repair |
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