糖尿病肾病病机演变规律初探

糖尿病肾病发病初始阶段,多以气阴两虚为主,临床表现以消渴证候为主;疾病发展到后期,则阴损及阳,伤及脾肾,脾肾阳虚,临床表现为水肿、虚劳、关格。气阴两虚是糖尿病肾病本虚之基本病机,在标实方面多以湿、热、瘀、毒之邪为主,瘀血贯穿于糖尿病肾病始终,湿热蕴结是加重糖尿病肾病不可忽视的方面。

Studies on Pathologic Evolution Law of Diabetes Nephropathy

In the initial phase of diabetes nephropathy,Qi-Yin Deficiency were key pathologicalsector.The main clinical feature presented diabetic symptoms;when it entered the later stage,deficiency of ying affecting yang were the main Pathogenesis.and then it affected spleen and kidney,caused Insufficiency of Spleen-Kidney-yang.The main clinical feature presented edema,consumptive disease,guange.Qi-Yin Deficiency were the basic root deficiency pathogenesis of diabetes nephropathy,and the main branch exdess patho genes is damp,heat,stasis,toxin.The stasis is the key throughout the evolution of diabetes nephropathy,and the damp-heat are the acute aggravated factors.