| 北苍术炮制前后挥发油部位保肝作用比较研究 |
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| 引用本文： | 沙多依,杭永付,宋菲,许瑞,丁选胜. 北苍术炮制前后挥发油部位保肝作用比较研究[J]. 现代中药研究与实践, 2010, 0(4): 41-43 |
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| 作者姓名： | 沙多依 杭永付 宋菲 许瑞 丁选胜 |
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| 作者单位： | 中国药科大学临床药学教研室,江苏南京210009 |
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| 摘 要： | 目的比较生苍术及麸炒苍术挥发油部位的保肝作用。方法提取制备生苍术和麸炒苍术挥发油;采用四氯化碳(CCl4)复制急性肝损伤模型,观察不同组别药物对小鼠血清转氨酶以及摄食量、饮水量、体重、肝、肾、脾、胸腺等脏器系数的影响。结果麸炒苍术挥发油组能显著降低小鼠血清AST和ALT水平。结论麸炒苍术挥发油部位的保肝作用强于生苍术。
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| 关 键 词： | 北苍术 生苍术 麸炒苍术 挥发油 保肝作用 |
Study on the Protecting-liver Effect of Volatile Oil of pre and post Processing Cangzhu |
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| SHA Duo-yi,HANG Yong-fu,SONG Fei,XU Rui,DING Xuan-sheng. Study on the Protecting-liver Effect of Volatile Oil of pre and post Processing Cangzhu[J]. Research and Practice on Chinese Medicines, 2010, 0(4): 41-43 |
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| Authors: | SHA Duo-yi HANG Yong-fu SONG Fei XU Rui DING Xuan-sheng |
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| Affiliation: | (Department of Clinical Pharmacy,China Pharmaceutical University,Nanjing 210009,China) |
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| Abstract: | Objective To compare the difference of protecting-liver effect between crude Cangzhu and processed Cangzhu.Methods The volatile oil of crude Cangzhu and processed Cangzhu were extracted separately.Liver injury model was made by CCl4 and food consumption,water consumption,body weight,some organ indexes （liver,kidney,spleen,thymus）,ALT,AST in serum were detected separately.Results Processed Cangzhu could decrease the contents of AST and ALT in serum.Conclusion The protecting-liver effect of volatile oil of processed Cangzhu was better than that of crude Cangzhu. |
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| Keywords: | North Cangzhu crude Cangzhu processed Cangzhu volatile oil protecting-liver effect |
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