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连翘对顺铂所致小鼠小肠推进的影响
引用本文:赵江红,白明,吴磊,赵喜兰,王宪龄.连翘对顺铂所致小鼠小肠推进的影响[J].河南中医药学刊,2010(4):683-683,686.
作者姓名:赵江红  白明  吴磊  赵喜兰  王宪龄
作者单位:[1]安阳市食品药品检验所,河南安阳455000 [2]河南中医学院,河南郑州450008 [3]漯河医药高等专科学校,河南漯河462002
摘    要:目的:通过连翘对顺铂所致小鼠小肠推进作用的影响以及量效关系的实验考察,验证其止吐功效。方法:采用炭末推进法对比各给药组间小鼠的小肠推进率。结果:3种剂量的连翘均有抑制小肠推进作用,抑制强度大小为连翘中剂量组〉连翘高剂量组〉连翘低剂量组〉盐酸昂丹斯琼组。结论:各给药组小肠推进率均受到抑制,以中剂量最为明显。

关 键 词:连翘  顺铂  小肠推进  小鼠  药效学实验

The Effect of Wort for Cisplatin Mice Intestine Propulsion
Zhao Jianghong,Bai Ming,Wu Lei,Zhao Xilan,Wang Xianling.The Effect of Wort for Cisplatin Mice Intestine Propulsion[J].Journal of Henan college of Traditional Chinese Medicine,2010(4):683-683,686.
Authors:Zhao Jianghong  Bai Ming  Wu Lei  Zhao Xilan  Wang Xianling
Institution:1. The Food and Drug Inspection of Anyang City,Anyang,Henan,China 455000 ;2.Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008;3. School of Henan Medicine Academy,Luohe,Henan,China 450008 )
Abstract:Objective:To explore the effects of Forsythiasuspense on small intestine propusion and dose-effect relation ship in mice(given DDP).Methods:carbon powder was used to observe the movement of small intestine in different dose in mice.Results:3 dose in mice can restrain small intestine in particular the middle-dose.conclusion:Forsythias uspense could restrain the small intestine propulsion function of mice.
Keywords:Forsythia suspense  DDP  intestina propulsion  mice  pharmacodynamics experiments
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