可吸收止血材料的生物相容性研究进展

可吸收止血材料是指用于伤口止血的可在体内降解吸收的生物医用材料，目前其在手术中止血发挥着重要作用。国内外近年来主要使用的可吸收止血材料包括壳聚糖、纤维蛋白原、α-氰基丙烯酸酯、氧化纤维素和胶原蛋白等，除止血效果外，其生物相容性正成为评价止血材料优劣的重要指标。在生物相容性的安全性和功能性原则指导下，对比它们在实验中的生物相容性结果，综合评价各类可吸收止血材料的生物相容性，为进一步研发良好生物相容性的可吸收止血材料以及日后的使用提供参考意见。

Progress in the Study on Biocompatibility of Absorbable Hemostatic Materials

Absorbable hemostatic materials are one of biomedical materials that applied to stanch bleeding. They are degradable in vivo and play an important role in the surgical hemostasis. In recent years, absorbable haemostatic materials mainly include chitosan, fibrinogen, cyanoacrylates, oxidized cellulose, collagen. Except for hemostatic effect, the biocompatibility is also an important feature for the quality of these materials. In this article, we made a comprehensive evaluation among the absorbable hemostatic materials under the guidance of safety and efficacy of biocompatibility, aiming to provide a valuable reference for the utility and development of absorbable hemostatic materials in further research.