Crossed cerebellar hyperperfusion on ictal FDG PET in astrocytoma |
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| Authors: | Michael Lin Tracy Smith Roy G. Beran |
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| Affiliation: | 1. Department of Neurology, First Affiliated Hospital of the University of South China, 69 Chuanshan Road, Hengyang, Hunan 421001, China;2. Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan 410008, China |
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| Abstract: | Crossed cerebellar hyperperfusion (CCH) is a rare phenomenon and reflects the close anatomical and functional relationship between the frontal brain region and its mediated remote effect on the contralateral cerebellum via the corticopontocerebellar pathway. Although it is well documented on cerebral single photon emission tomography (SPECT) in patients with epilepsy, it is rarely observed in seizures originating from brain tumours. We report a 41-y-old man who whilst undergoing 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for investigation of suspected glioma, developed a generalized seizure. The scan performed shortly after seizure onset demonstrated intense metabolic activity in the right superior frontal lobe and in the contralateral cerebellar hemisphere consistent with CCH. |
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