Symmetrical brainstem encephalitis caused by herpes simplex virus |
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| Authors: | Shiroh Miura Takashi Kurita Kazuhito Noda Mitsuyoshi Ayabe Hisamichi Aizawa Takayuki Taniwaki |
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| Institution: | 1. Service de neurologie, hôpital Louis-Pasteur, BP 30407, 28018 Chartres cedex, France;2. Clinique de neurologie, CHNU de Fann, BP 5035, Dakar, Senegal;1. Department of Emergency Medicine, University of California, San Francisco, CA;2. Department of Emergency Medicine, University of Southern California, Los Angeles, CA;1. Department of Bio-Medical Sciences, University of Catania, V. Androne, 81, 95123 Catania, Italy;2. Clinical Virology Unit, A.O.U. “Policlinico-Vittorio Emanuele”, P.O. “Gaspare Rodolico”, V. S. Sofia, 78, 95123 Catania, Italy;3. O.U. Radiodiagnostic and Oncologic Radiotherapy, A.O.U. “Policlinico-Vittorio Emanuele”, P.O. “Gaspare Rodolico”, V. S. Sofia, 78, 95123 Catania, Italy;4. O.U. Anesthesia and Intensive Care, A.O.U. “Policlinico-Vittorio Emanuele”, P.O. “Gaspare Rodolico”, V. S. Sofia, 78, 95123 Catania, Italy;5. Department “G.F. Ingrassia”, University of Catania, V. S.Sofia, 87, 95123 Catania, Italy |
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| Abstract: | We describe a 53-year-old man with herpes simplex virus (HSV) brainstem encephalitis diagnosed based by positive HSV immunoglobulin M antibodies from cerebrospinal fluid. The MRI findings of this case had three unique features. First, the lesions were symmetrical. Second, the lesions may have been associated with reactivation of HSV infection in the region of the trigeminal nerve. Third, diffusion-weighted and apparent diffusion coefficient (ADC) imaging, conducted for the first time on an HSV brainstem encephalitis case, suggested that the lesions were associated with vasogenic edema. |
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