Hemicellulose dressing versus rayon dressing in the re-epithelialization of split-thickness skin graft donor sites: a multicenter study |
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| Authors: | Lydia M Ferreira Leila Blanes Alfredo Gragnani Daniela F Veiga Frederico P Veiga Gilka B Nery Gustavo Henrique HR Rocha Heitor C Gomes Mario G Rocha Regina Okamoto |
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| Institution: | 1. Division of Plastic Surgery, Federal University of São Paulo – UNIFESP, Rua Napoleão de Barros 715, 4. andar, Vila Clementino, 04023-062 São Paulo, SP, Brazil;2. Samuel Libânio Hospital –Sapucaí Valley University – UNIVÁS, MG, Brazil;3. Burns Unit of Santa Casa of São José dos Campos, SP, Brazil;4. Vila Penteado General Hospital, SP, Brazil;5. Pirajussara General Hospital/UNIFESP, SP, Brazil;1. Department of Oral and Maxillofacial Surgery (Head: Prof. Dr. Max Heiland), University Medical Center Hamburg-Eppendorf, Martinistr. 52, Hamburg 20246, Germany;2. Department of Oral and Maxillofacial Surgery (Head: PD Dr. Dr. Wolfgang Eichhorn), General Hospital Balingen, Balingen, Germany;3. Department of Neurology (Head: Prof. Dr. Christian Gerloff), University Medical Center Hamburg-Eppendorf, Hamburg, Germany;1. Norwegian University of Science and Technology(NTNU), Trondheim, Norway;2. Department of Pulp and Paper Industries, Faculty of Wood and Paper Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran;3. Paper and Fiber Research Institute (PFI), Høgskoleringen 6b, Trondheim 7491, Norway;1. Departamento de Química Inorgánica e Ingeniería Química, Facultad de Ciencias, Campus Universitario de Rabanales, Universidad de Córdoba, 14071 Córdoba, Spain;2. Departamento de Informática y Análisis Numérico, Escuela Politécnica Superior, Campus Universitario de Rabanales, Universidad de Córdoba, 14071 Córdoba, Spain;3. Departamento de Bioquímica y Biotecnología, Facultad de Enología, Campus Sescelades, Universitat Rovira i Virgili, 43007 Tarragona, Spain;1. Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera en México, Coyoacan, México;2. Servicio de Glaucoma, Hospital Dr. Luis Sánchez Bulnes, Coyoacan, México |
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| Abstract: | The aim of this study was to compare the effectiveness of a hemicellulose dressing with that of rayon dressing in the healing of split-thickness skin graft donor sites. Twenty-eight patients were selected from five different hospitals and randomized into two groups: hemicellulose dressing group and rayon dressing group. All patients underwent split-thickness skin grafting for various reasons, and the skin graft donor site wounds were covered with hemicellulose dressing (n = 14) or rayon dressing (n = 14). The donor site was assessed on postoperative days 1, 7, 14, 21, and 28 for hyperemia, pruritus, pain, exudate level, and adherence of the wound dressing. At the 60-day follow-up visit, the donor site was assessed again for pruritus and pain. Touch-pressure, thermal, and pain sensibility tests were performed preoperatively and on postoperative day 60 together with the assessment of color and texture of the re-epithelialized area. In all patients, re-epithelialization was completed between 14 and 21 days after surgery. There were no significant differences between the two groups with regard to pain, hyperemia, pruritus, exudate, and final appearance (color and texture) of the skin graft donor site. The rayon dressing provided significantly better adherence than the hemicellulose dressing, and both dressings showed similar results with regard to the parameters evaluated when used in the treatment of split-thickness skin graft donor sites. |
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