石榴皮乙醇提取物对小鼠细胞免疫功能的影响 |
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引用本文: | 吕琴. 石榴皮乙醇提取物对小鼠细胞免疫功能的影响[J]. 中医临床研究, 2013, 0(10): 43-45 |
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作者姓名: | 吕琴 |
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作者单位: | 新疆医科大学护理学院,新疆 乌鲁木齐,830000 |
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摘 要: | 目的:探讨石榴皮乙醇提取物对小鼠细胞免疫功能的影响。方法:通过腹腔注射环磷酰胺建立免疫抑制动物模型,应用石榴皮乙醇提取物、石榴皮总黄酮提取物对免疫抑制的小鼠进行治疗,观察两种提取物对小鼠巨噬细胞吞噬功能、脾淋巴细胞转化功能的影响。结果:石榴皮乙醇提取物中剂量组和高剂量组及石榴皮总黄酮提取物组能增强小鼠腹腔巨噬细胞的吞噬功能,高剂量组能够增强小鼠脾淋巴细胞转化功能(P<0.01)。结论:石榴皮乙醇提取物对免疫抑制小鼠的细胞免疫功能具有一定的提高作用。
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关 键 词: | 石榴皮乙醇提取物 石榴皮总黄酮 免疫抑制 细胞免疫 |
Effects of ethanol extraction from pomegranate peel on cellular immune function in mice |
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Abstract: | Objective: To investigate effcts of pomegranate rind ethanol extract on the function of immune cells. Methods: Established immunosuppressed animal models by intraperitoneal injection of cyclophosphamide, the application of pomegranate peel ethanol extract, pomegranate rind total flavonoids extract on mice immunosuppressive treatment to observe the two extracts murine macrophage phagocytosis, spleen lymphocyte transformation function. Results: Middle-dose group and high-dose group and pomegranate rind of pomegranate peel ethanol extract of total flavonoids extracted group can enhance the phagocytic function of mouse peritoneal macrophages, the high-dose group can enhance mouse spleen lymphocyte transformation function (P〈0.01). Conclusion: Pomegranate peel ethanol extract on cellular immune function of immunosuppressed mice has improved to some extent. |
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Keywords: | Pomegranate peel ethanol extract Pomegranate rind total flavonoids Immunosuppression Cellular immunity |
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