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| 基于pADM的组织工程化皮肤修复新西兰兔皮肤损伤 | |
| 引用本文： | 但卫华,关林波,李凯,刘学旭,王康建,但年华,林海,米贞建.基于pADM的组织工程化皮肤修复新西兰兔皮肤损伤[J].四川医学,2010,31(11):1573-1575. |
| 作者姓名： | 但卫华 关林波 李凯 刘学旭 王康建 但年华 林海 米贞建 |
| 作者单位： | 1. 四川大学制革清洁技术国家工程实验室,四川,成都,610065;四川大学生物医学工程技术研究中心,四川,成都,610065;成都佰乐金生物科技有限公司,四川,成都,610041 2. 四川大学制革清洁技术国家工程实验室,四川,成都,610065;四川大学生物医学工程技术研究中心,四川,成都,610065 3. 核工业416医院整形美容创伤外科,四川,成都,610051 4. 四川大学动物实验中心,四川,成都,610041 5. 成都佰乐金生物科技有限公司,四川,成都,610041 |
| 基金项目： | 成都市科技计划资助项目 |
| 摘 要： | 目的初步探讨组织工程化真皮在兔皮肤损伤修复中的作用。方法利用组织工程化真皮移植法进行兔皮肤损伤修复,观察修复过程,比较其修复效果,并进行组织学观察和BrdU免疫组化染色观察。结果实验组修复效果优于空白组,实验组愈合时间为（18.2±3.8）d,空白组为（28±2.3）d。结论猪脱细胞真皮基质材料具有良好的生物相容性和功能性,具有优良的体表创伤修复潜力;构建组织工程化真皮亦是一种有潜力的人体体表创伤修复方法。 |
| 关 键 词： | 兔皮肤 猪脱细胞真皮基质 组织工程化皮肤 创伤修复 |
Study on injured skin in new zealand rabbits healing with tissue-engineering skin based pADM |
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| DAN Wei-hua,GUAN Lin-bo,LI Kai,et al..Study on injured skin in new zealand rabbits healing with tissue-engineering skin based pADM[J].Sichuan Medical Journal,2010,31(11):1573-1575. | |
| Authors: | DAN Wei-hua GUAN Lin-bo LI Kai |
| Institution: | DAN Wei-hua1,2,GUAN Lin-bo1,LI Kai3,et al.1.National Engineering Laboratory for Clean Technology of Leather Manufacture,Sichuan University,Chengdu,Sichuan 610065,2.The Research Center of Biomedicine Engineering,Sichuna University,3.The 416 Hospital of China Nuclear Industry Ministry,Sichuan 610051,China |
| Abstract: | Objective Preliminary research the tissue engineered skin material in the process of rabbit skin wound rehabilitation.Methods The porcine acellular dermal matrix(pADM) based tissue engineering materials which were prepared with rabbit fibroblast were employed to the healing of skin wound.The processes were observed and compared with the control where pADM were applied,and the histological method and BrdU immunohistochemical staining were wtilized.Results The healing time of experimental group,which was(18.2... |
| Keywords: | rabbit skin porcine acellular dermal matrix(pADM) tissue engineering skin wound healing |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |