| 麻桂解表颗粒的退热作用的实验研究 |
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| 引用本文： | 刘希飒,吴林彬,冯玛莉,裴小静.麻桂解表颗粒的退热作用的实验研究[J].山西中医学院学报,2005,6(4):8-9. |
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| 作者姓名： | 刘希飒 吴林彬 冯玛莉 裴小静 |
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| 作者单位： | 山西省中医药研究院,山西,太原,030012;山西省食品药品监督管理局,山西,太原,030021 |
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| 基金项目： | 山西省卫生厅科技发展计划资助项目（项目编号：041048-3） |
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| 摘 要： | 目的:观察麻桂解表颗粒的退热作用。方法:用2,4-二硝基苯酚和大肠杆菌内毒素分别制成发热大鼠模型各40只。每种模型分为5组,每组8只,分别给予生理盐水,阿斯匹林和麻桂解表颗粒低、中、高剂量,记录发热大鼠不同时间的体温。结果:麻桂解表颗粒低、中、高剂量均可显著降低发热大鼠模型的体温。结论:麻桂解表颗粒对化学性致热、内毒素致热大鼠均有明显退热作用,随剂量增加,起效时间缩短。
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| 关 键 词： | 麻桂解表颗粒 大肠杆菌内毒素 2 4-二硝基苯酚 退热 |
| 文章编号： | 1670-0258（2005）04-0008-02 |
| 收稿时间： | 2005-09-07 |
| 修稿时间： | 2005-10-12 |
Experimental Study on Antipyretic Effect of Magui Jiebiao Granule |
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| Liu Xisa et al.Experimental Study on Antipyretic Effect of Magui Jiebiao Granule[J].Journal of Shanxi College of Traditional Chinese Medicine,2005,6(4):8-9. |
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| Authors: | Liu Xisa |
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| Institution: | Academy of TCM and Pharmacology,Taiyuan Shanxi 030021 |
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| Abstract: | Objective:To explore the antipyretic effect of Magui Jiebiao Granule(MJG).Methods:The febrile model rats were induced by 2,4-dinitrophenol(model 1)and coleoceles'endotoxin(model 2).Model 1(n=40)and model 2(n=40)respectively were randomized into five groups(n=8).Then five groups were ig with normal saline,70 mg/kg of aspirin and 1.0 g/kg,2.0 g/kg,4.0 g/kg of MJG.The rats'temperatures were recorded.Results:MJG can decrease the temperature of the febrile rats.Conclusion:MJG has significant antipyretic effect,which relate with the dosage. |
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| Keywords: | Magui Jiebiao Granule colitoxin 2 4-dinitrophenol antipyretic effect |
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