| 鬼针草总黄酮缓释片处方工艺优选 |
| |
| 引用本文： | 杜利月,崔燕兵,郭留城.鬼针草总黄酮缓释片处方工艺优选[J].中国实验方剂学杂志,2013,19(14):67-70. |
| |
| 作者姓名： | 杜利月 崔燕兵 郭留城 |
| |
| 作者单位： | 漯河医学高等专科学校,河南漯河,462002 |
| |
| 摘 要： | 目的:优选鬼针草总黄酮缓释片的处方工艺.方法:以羟丙基甲基纤维素-K4M(HPMC-K4M)为骨架材料,淀粉和乳糖为填充剂,3个时间点的总黄酮累积释放度为综合评价指标,在单因素试验基础上,采用正交试验考察HPMC-K4M用量、淀粉-乳糖、片剂硬度和抗黏剂用量对缓释片处方工艺的影响.结果:最佳处方工艺为HPMC-K4M用量50％,淀粉-乳糖(2∶1),2％微粉硅胶为抗黏剂,片剂硬度5 kg· mm-2.结论:该工艺稳定可行,制粒、压片及缓释情况均良好,制成的片剂符合相关规定.
|
| 关 键 词： | 鬼针草 总黄酮 缓释片 单因素试验 正交试验 |
| 收稿时间： | 2013/1/31 0:00:00 |
Optimization of Formulation Technology of Total Flavonoids from Bidens bipinnata Sustained Release Tablets |
| |
| DU Li-yue,CUI Yan-bing and GUO Liu-cheng.Optimization of Formulation Technology of Total Flavonoids from Bidens bipinnata Sustained Release Tablets[J].China Journal of Experimental Traditional Medical Formulae,2013,19(14):67-70. |
| |
| Authors: | DU Li-yue CUI Yan-bing and GUO Liu-cheng |
| |
| Institution: | Luohe Medical College, Luohe 462002, China;Luohe Medical College, Luohe 462002, China;Luohe Medical College, Luohe 462002, China |
| |
| Abstract: | |
| |
| Keywords: | Bidens bipinnata total flavonoids sustained release tablets single factor test orthogonal test |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《中国实验方剂学杂志》浏览原始摘要信息 |
| 点击此处可从《中国实验方剂学杂志》下载免费的PDF全文 |
|
