| 高血糖大鼠海马CA1区一氧化氮合成酶阳性神经元变化的研究 |
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| 引用本文： | 周郦楠,王冶,孙永杰. 高血糖大鼠海马CA1区一氧化氮合成酶阳性神经元变化的研究[J]. 中国组织工程研究与临床康复, 2002, 6(8): 1232 |
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| 作者姓名： | 周郦楠 王冶 孙永杰 |
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| 作者单位： | Occupation and Technology College，Liaoning Chinese Medicine College，Shenyang 110005，China |
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| 摘 要： | Nitricoxide（NO）isanewneurotransmitter，existsincentralnervoussystemwidelyandtakespartinnerveconductionandreg－ulationofcerebralbloodstream犤１犦．Butthechangeofnitricoxidesynthetase（NOS）positiveneuronshasn＇tbeenreportedindetail．WeadopthistochemicalmethodtoobserveNOSpositiveneuronsinhippocampusCA１ofratswithhyperglycemia．１Materialsandmethods１．１GroupsandanimalmodelsDivide４０Wistarratsweighted２００～２５０ginto３groups．Normalcontrolgroup（NC）：２０rats．Hyperglycemiagroup（D…
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Investigation on the change of nitric oxide synthetase positive neurons in hippocampus CA1 area of rats with hyperglycemia |
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| ZHOU Li nan,WANG Ye,SUN Yong jie. Investigation on the change of nitric oxide synthetase positive neurons in hippocampus CA1 area of rats with hyperglycemia[J]. Journal of Clinical Rehabilitative Tissue Engineering Research, 2002, 6(8): 1232 |
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| Authors: | ZHOU Li nan WANG Ye SUN Yong jie |
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| Abstract: | Objective To observe the expression of nitric oxide syhthetase(NOS) in hippocampus CA1 neurons with hyperglycemia.Method NADPH d histochemical method was used.Rcsults NOS positive neurons expressed in hippocampus CA1 and nomal neurons of 6 weeks old rats with hyperglycemia(DM) and normal rats(NC).There was significant difference in neurons between DM group and control group.Conclusion NOS positive neurons decrease in hippocampus CA1 of rats with hyperglycemia. |
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| Keywords: | hyperglycemia nitric oxide synthetase hippocampus rat |
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