依达拉奉对高龄缺血性脑卒中患者颅内动脉血流动力学的影响

目的:观察依达拉奉注射液对高龄急性脑梗死患者颅内动脉血流动力学的影响及评价其临床疗效.方法:选择符合标准的急性脑梗死患者共152例,随机分为治疗组和对照组,观察依达拉奉治疗30 d后的临床疗效及药物对急性脑梗死患者血液流变学的影响.结果:治疗组经依达拉奉治疗后与对照组比较,中国卒中量表(CSS)评分差异有统计学意义(P＜0.05)；治疗组高龄急性脑梗死患者在疗效和各项血液流变学指标上,都优于对照组；治疗组患者治疗后即刻和治疗后7d的侧枝循环代偿改善率均优于对照组(P＜0.05).结论:依达拉奉治疗高龄急性脑梗死疗效确切,它能有效改善患者颅内动脉血流动力学,提高神经功能.

Influence of Edaravone on Intracranial Artery Hemodynamics in Advanced Age Patients with Acute Cerebral Infarction

Objective: To observe the effects of edaravone on intracranial artery hemodynamics and acute cerebral infarction in advanced age patients. Method: One hundred and fifty-two cases with acute cerebral infarction patients were randomLy divided into treatment group and control group, the clinical efficacy of edaravone on acute cerebral infarction and blood rheology were observed after for treatment of 30 days. Result: In the treatment group, compared with control group the difference between Chinese stroke scale(CSS) score was statistically significant (P<0.05).The efficacy and the hemorheological indexes in treatment group were better than control group in advanced age patients with acute cerebral infarction.The immediate and after 7 d collateral circulation compensation improvement rate in the treatment group patients after treatment were better than control group (P<0.05). Conclusion: Edaravone has accurate curative effects, it can effectively improve the intracranial arterial hemodynamics of patients and the nerve function.