| 不同浓度氮酮对复方雷公藤贴片中阿魏酸体外透皮吸收的影响 |
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| 引用本文： | 杨柳,冯星,巫志峰,杨华中,周源,王茜,刘英姿.不同浓度氮酮对复方雷公藤贴片中阿魏酸体外透皮吸收的影响[J].湖南师范大学学报(医学版),2005,2(1):15-17. |
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| 作者姓名： | 杨柳 冯星 巫志峰 杨华中 周源 王茜 刘英姿 |
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| 作者单位： | 广东省中医院,广东,广州,510120;湖南师范大学医学院,湖南,长沙,410006 |
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| 摘 要： | 目的:研究氮酮对复方雷公藤贴片中阿魏酸体外透皮吸收的影响。方法:以大鼠腹部剑突以下皮肤为实验屏障,观察氮酮浓度(体积比)分别为0、0 .5 %、1%、2 %时阿魏酸透皮吸收速率常数。结果:氮酮可以促进阿魏酸的透皮吸收。结论:在实验浓度范围内,氮酮浓度为1%时有最大吸收。
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| 关 键 词： | 氮酮 复方雷公藤贴片 阿魏酸 体外透皮吸收 |
| 文章编号： | 1673-016x(2005)01-0015-03 |
| 修稿时间： | 2004年11月5日 |
Effects of Azone of Different Concentration in Formula Leigongteng TDD on the Transdermal Absorption of Ferric Acid in vitro |
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| YANG Liu,FENG Xing,WU Zhi-feng,YANG Hua-zhong,ZHOU Yuan,WANG Qian,LIU Ying-zi.Effects of Azone of Different Concentration in Formula Leigongteng TDD on the Transdermal Absorption of Ferric Acid in vitro[J].Journal of Hunan Normal University(Medical Science),2005,2(1):15-17. |
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| Authors: | YANG Liu FENG Xing WU Zhi-feng YANG Hua-zhong ZHOU Yuan WANG Qian LIU Ying-zi |
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| Institution: | YANG Liu1,FENG Xing 2*,WU Zhi-feng1,YANG Hua-zhong2,ZHOU Yuan2,WANG Qian2,LIU Ying-zi2 |
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| Abstract: | Objective To study the effects of azone of diffe rent concentration in TDD on th e transdermal absorption of ferric acid (FA). Methods The skin of the abdomen o f rats below the ribs was used as experimental barrier to study the transdermal absorption constant of FA under azone with different concentration of 0, 0.5%, 1 % or 2%. Results Azone can accelerate the transdermal absorption of FA. Conclusion Within the above-mentioned concentration range i n vitro, 1% of azone exhibits the maximal absorption. |
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| Keywords: | azone Formula Leigongteng TDD ferric acid transderma l absorption in vitro |
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