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水泥型羟基磷灰石人工骨的制备及性能分析(英文)
引用本文:同志超,陈君长,王坤正,同志勤,党晓谦,李毅,白斌,时志斌.水泥型羟基磷灰石人工骨的制备及性能分析(英文)[J].南京医科大学学报(英文版),2003(5).
作者姓名:同志超  陈君长  王坤正  同志勤  党晓谦  李毅  白斌  时志斌
作者单位:西安交通大学第二医院骨科,西安交通大学第二医院骨科,西安交通大学第二医院骨科,西安交通大学第二医院骨科,西安交通大学第二医院骨科,西安交通大学第二医院骨科,西安交通大学第二医院骨科,西安交通大学第二医院骨科 西安 710004,中国,西安 710004,中国,西安 710004,中国,西安 710004,中国,西安 710004,中国,西安 710004,中国,西安 710004,中国,西安 710004,中国
基金项目:Supported by Grant from the shaanxi Provincial Science and Technology Foundation(2000K_(14)-G_(16))
摘    要:目的:制备水泥型羟基磷灰石人工骨,并进行性能分析。方法:高温法制备出磷酸四钙,然后在模拟体内环境下将其与无水磷酸氢钙发生水化固化反应,合成水泥型羟基磷灰石人工骨,采用X线衍射、扫描电镜观察、体积密度、吸水率、孔隙率及耐压强度测量进行性能分析。结果:该人工骨主要成分为低结晶度的羟基磷灰石;微观结构呈针状或花瓣状晶体构成,微孔直径约4-10 μm,孔隙相互交通;平均体积密度为1.922 g·cm~(-3);平均吸水率为15.503%;孔隙率为29.777%;耐压强度为42.70 MPa。结论:本研究所制人工骨具有三维空间结构,力学性能符合人体非负重骨植骨要求。

关 键 词:CPC人工骨  羟基磷灰石  制备

Preparation of Hydroxyapatite Cement and Analy-sis as of its Disposition
TONG Zhi-chao,CHEN Jun-chang WANG Kun-zheng,TONG Zhi-qin,DANG Xiao-qian LI Yi,BAI Bin,SHI Zhi-bin.Preparation of Hydroxyapatite Cement and Analy-sis as of its Disposition[J].Journal of Nanjing Medical University,2003(5).
Authors:TONG Zhi-chao  CHEN Jun-chang WANG Kun-zheng  TONG Zhi-qin  DANG Xiao-qian LI Yi  BAI Bin  SHI Zhi-bin
Institution:TONG Zhi-chao,CHEN Jun-chang WANG Kun-zheng,TONG Zhi-qin,DANG Xiao-qian LI Yi,BAI Bin,SHI Zhi-bin Department of Orthopedics,the Second Hospital of Xi'an Jiaotong University,Xi'an 710004,P. R. China
Abstract:Objective: To prepare hydroxyapatite cement (or calcium phosphate cement, CPC) and analyze its capability. Methods: Tetracalcium phosphate (TTCP) was prepared by the method of high heat. TTCP reacted with in simulated body situation and produced CPC, Its capability was analyzed by scanning electron microscopy (SEM) , X-ray diffraction(XRD). Its density, absorbing water coefficient, macroporosity and campressive strength were measured also. Results: The main element of CPC is hydroxyapatite (HA) , its microstructure comprised of needlelike or petal crystals. The diameter of micropore was 4-10 nm, density was 1.922 g/cm3, macroporosity was 29. 777% , absorbing coefficient was 15. 503%, compressive strength was 42. 70 Mpa. Conclusion: This CPC has three-dimensional spatial structure, its strength meets the need of cancellous bone grafting.
Keywords:hydroxyapatite cement bone substitute  hydroxyapatite  prepare
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