Pulmonary infiltrates and fever induced by isoniazid |
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Authors: | E R Salomaa E L Ruokonen K Tevola E Tala |
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Institution: | Department of Diseases of the Chest, University Central Hospital of Turku, Preitilä, Finland. |
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Abstract: | An 88 year old woman with bacteriologically confirmed pulmonary tuberculosis was first treated with isoniazid, rifampicin and pyrazinamide. Two weeks later she developed pulmonary infiltrates with fever. A drug-induced reaction was suspected but the reaction recurred three times until isoniazid was identified as the cause. The reaction became worse each time, finally being nearly fatal. |
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