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蛇床子化学成分及抗肿瘤活性的研究进展
引用本文:周则卫,刘培勋.蛇床子化学成分及抗肿瘤活性的研究进展[J].中国中药杂志,2005,30(17):1309-1313.
作者姓名:周则卫  刘培勋
作者单位:中国医学科学院,放射医学研究所,天津,300192
摘    要:中药蛇床子Cnidium momnieri的主要药理活性成分是香豆素类化合物和挥发油,另外还含有单萜多醇,糖类成分,以及近来新发现的倍半萜类成分等。近年来国内外对蛇床子抗肿瘤活性的研究较为活跃,其抗肿瘤作用是多方面的综合作用,包括直接的抑瘤作用,抗突变活性,逆转肿瘤多药耐药性,以及免疫增强作用等。综述了近10年来国内外对蛇床子的化学成分,抗肿瘤作用及相关方面的研究进展,以促进蛇床子抗肿瘤研究的深入。

关 键 词:蛇床子  化学成分  抗肿瘤
文章编号:1001-5302(2005)17-1309-05
收稿时间:9/5/2004 12:00:00 AM
修稿时间:2004-09-05

Progress in study of chemical constituents and anti-tumor activities of Cnidium monnieri
ZHOU Ze-wei;LIU Pei-xun.Progress in study of chemical constituents and anti-tumor activities of Cnidium monnieri[J].China Journal of Chinese Materia Medica,2005,30(17):1309-1313.
Authors:ZHOU Ze-wei;LIU Pei-xun
Institution:Chinese Academy of Medical Sciences, Tradiation Medica Institute, Tianjin 300192, China. zhouzewei666@yahoo.com.cn
Abstract:The main pharmacological constituents of Chinese traditional medicine herb Cnidium monnieri are coumarin compounds and volatile oil. In addition, it contains monoterpene polyols, glucides, as well as recently discovered sesquiterpene components. In recent years, rather active investigations of its anti-tumor were performed at home and abroad. C. monnieri possesses multi-aspect and comprehensive anti-tumor functions, involving directly tumor-inhibitory activity, anti-mutagenicity, reversing multi-drug tolerance of tumor, as well as improving immune functions and so on. In this review, chemical constituents, anti-tumor activities and relevant investigations of Fructus Cnidii were summarized recent decade.
Keywords:Cnidium monnieri  chemical constituents  anti-tumor activities
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