糖尿病性神经病的体感诱发电位分析

对２６例Ⅱ型糖尿病患者进行体感诱发电位（ＳＥＰ）检测，以了解其神经病变（ＤＮＰ）情况。结果：依临床表现诊断有工发症患者５４％，ＳＥＰ异常７６．９％，其中上肢异常５０％，下肢异常９０％。主要表现为上肢Ｎ９和下肢Ｐ４０潜伏期明显延长，Ｎ９平均峰潜伏期男１２．３ｍｓ，ｓ：０．８６，Ｐ〈０．００１，女分别为１１．６ｍｓ，０．８８，Ｐ〈０．００２；Ｐ４０平均峰值伏期男４５．７ｍｓ，ｓ：４．５５，Ｐ〈０．００

Somatosensory Evoked Potential Testing in Diabetic Neuropathy

Somatosensory evoked potential (SEP) was tested in 26 patients with non-insulin dependent diabetes (NIDD) to study diabetic neuropathy (DNP). Fourteen cases were clinically diagnosed having DNP (54% ), 20 cases were abnormal on SEP (76. 9 % ). Among the 20 cases, SEP following median nerve stimulation were studied in 10 patients (50%) ; SEP following posterior tibial nerve stimulation were studied in 18 patients (90%). In median nerve SEP. the peak latency of N9 showed a significant delay; in posterior tibial nerve SEP. the peak latency of P40 showed a significant delay in comparison with normal values of our laboratory. The mean N9 peak latency of male:12. 3 ms, s: 0. 86. P<0. 001 and of female: 11. 6 ms, s: 0. 88, P<0.002. The mean P40 peak latency of male:45. 7 ms, s: 4. 55, P<0. 002 and of female: 40. 2 ms, s: 0. 79. P<0.002. As Comparing with normal values,there was a significant difference in mean N9 peak latency and mean P40 peak latency. Peak latency of N9 and P40 showed a significant positive correlation with the level of recent blood glucose of the patients with the correlation co-efficient (r) being 0. 8532 and 0. 5580 respectively (P<0.001, one side test). The higher the level of recent blood glucose of the patients was. the more obvious the SEP abnormal, In addition, only amplitude was reduced in the slight disorder, while in the serious cases, both amplitude reduced and peak latency delayed. The findings suggest that SEP may helpful to the clinical diagnosis of DNP and make the circumstance of DNP known to us.