儿童阻塞性睡眠呼吸暂停综合征的主要病因及治疗

目的：探讨儿童阻塞性睡眠呼吸暂停低通气综合征(Obstructive sleep apnea hypopnea syndrome,OSAHS)的临床特征和治疗措施。方法:分析20例儿童OSAHS的发病原因和机理，并以随机抽取的48例接受手术治疗的不伴鼾症的慢性扁桃体炎病人作对照。结果:腺样体和扁桃体肥大是儿童OSAHS的主要发病原因，不存在悬雍垂和软腭的松弛和肥厚。发病组的生长发育明显迟缓于对照组，因而与肥胖无联系。结论：儿童OSAHS的发病原因和机理不同于成人，悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)不适合于儿童OSAHS。

Principal pathogenesis and treatments for obstructive sleep apnea syndrome in children

Objective To explore the clinical characteristics and treatments for obstructive sleep apnea hyponea syndrome (OSAHS) in children. Methods Pathogenesis of 40 children with OSAHS were analyzed, and were compared with 48 patients who had no history of snoring but underwent tonsillectomy for chronic tonsillitis. Results Adenotonsillar hypertrophy could play an important role in the pathogenesis of OSAHS in children. There was no relaxation of uvula and soft palate. Significant difference of growth was found between patients who snore and who did not. No correlation with obesity was found. Conclusion Pathogenesis of OSAHS in children is different from that in adults. Uvulopalatopharyngoplasty (UPPP) does not fit OSAHS in children.