妇宁康片的质量标准研究

目的：建立妇宁康片的质量控制方法。方法：薄层色谱法对人参、赤芍、蛇床子、当归、黄柏进行定性鉴别；高效液相色谱法对淫羊藿苷进行含量测定，以Diamonsil^TM C18（200mm×4．6mm，5μm）为分析柱，乙腈-水（26：74）为流动相；流速：1．0ml·min^-1；检测波长：270nm。结果：薄层色谱中均能明显地检出人参、赤芍、蛇床子、当归、黄柏，淫羊藿苷在0．043～0．517μg·ml^-1范围内，浓度与峰面积呈良好的线性关系，r=0．9999，平均回收率为99．4％，RSD=1．8％（n=6）。结论：本法简便，准确，专属性强，可以作为该制剂的质量控制方法。

Study on Quality Standard for Funingkang Tablets

Objective： To establish a method for the quality control of funingkang tablets. Method： Radix et rhizome Ginseng, radix paeoniae rubra,fruetus enidii, angelica sinensis and phellodendron chinense were identified by TLC. HPLC for determination of icariin was conducted on a DiamonsilTM Cls column （200 mm ×4. 6 mm,5μm） with aeetonitrile - water （26： 74） as mobile phase at the flow rate of 1.0 ml·min^-1, and the detection wavelength was set at 270 nm. Result： The calibration curve of ieariin was linear within the range of 0. 04343. 517 μg·ml^-1 （ r = 0. 999 9 ）. The average recovery was 99.4% with/LSD of 1.8 % （ n = 6 ）. Conclusion： The method is simple, accurate, and suitable for the quality control of funingkang tablets.