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探讨血小板相关参数变化及D二聚体对诊断脑梗死的临床意义
引用本文:闫伟,李斌,张周良,张惠中.探讨血小板相关参数变化及D二聚体对诊断脑梗死的临床意义[J].中国血液流变学杂志,2010,20(4):658-659.
作者姓名:闫伟  李斌  张周良  张惠中
作者单位:第四军医大学唐都医院检验科,陕西西安710038
摘    要:目的 探讨平均血小板体积(MPV)、大血小板比率(P-LCR)及D二聚体(DD)对诊断腑梗死的临床意义.方法 以脑梗死患者60例为实验组,测定其全血MPV、P-LCR和血浆DD,并与54名正常对照组进行比较分析,结果脑梗死患者MPV,P-LCR显著高于对照组(P<0.01);血浆DD含量明显高于对照组(P<0.05).结论 测定MPV、P-LCR及DD对于脑梗死的诊断和病情判断均有重要的指导意义,尤其是MPV和P-LCR更显著、更敏感.

关 键 词:脑梗死  平均血小板体积  大血小板比率  D二聚体

Application Value of Platelet-related Parameters and D-dimer in the Diagnosis of Cerebral Infarction
YAN Wei,LI Bin,ZHANG Zhou-liang,ZHANG Hui-zhong.Application Value of Platelet-related Parameters and D-dimer in the Diagnosis of Cerebral Infarction[J].Chinese Journal of Hemorheology,2010,20(4):658-659.
Authors:YAN Wei  LI Bin  ZHANG Zhou-liang  ZHANG Hui-zhong
Institution:( Department of Clinical Laboratory, Tangdu Hospital,The Fourth Military Medical University, Xi'an 710038,China )
Abstract:Objective Application value of mean platelet volume(MPV),percentage of large platelets(P- LCR) and D dimer(DD) in the diagnosis of cerebral infarction. Methods 60 patients with cerebral infarction as the experimental group,measured in whole blood MPV, P-LCR and plasma DD,and with 54 normal controls were analyzed. Results MPV, P-LCR were significantly higher in experimental group than in control groups(P〈0.01);Plasma DD were significantly higher(P〈0.05).Conclusion The determination of MPV, P-LCR and DD conditions for cerebral infarction has important guiding significance to diagnose and judge disease condition,especially in MPV and P-LCR more significantly, more sensitive.
Keywords:cerebral infarction  mean platelet volume  large platelet ratio  D-dimer
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