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产后溶血性尿毒症性综合征的临床表现及处理——3例病例分析及文献复习
引用本文:赫英东,吕继成,陈倩.产后溶血性尿毒症性综合征的临床表现及处理——3例病例分析及文献复习[J].中华围产医学杂志,2010,13(2).
作者姓名:赫英东  吕继成  陈倩
作者单位:1. 北京大学第一医院妇产科,100034
2. 北京大学第一医院肾内科,100034
摘    要:目的 探讨产后溶血尿毒症性综合征(postpartum hemolytic uremic syndrome,PHUS)的临床特征、诊断、治疗及预后. 方法 结合3例PHUS病例,复习有关文献,讨论PHUS的临床特征、诊断治疗及预后. 结果 3例患者均于剖宫产分娩后3 d内出现微血管病性溶血性贫血、血小板减少、肾功能急剧恶化.经血浆置换及血液透析等治疗病情稳定.发病后随访至今,1例患者肾功能恢复正常,2例仍需血液透析维持. 结论 早期诊断和及时正确治疗对于降低PHUS患者的病死率至关重要.

关 键 词:产后期疾病  溶血尿毒症综合征  紫癜  血栓性血小板减少性  诊断

Postpartum hemolytic uremic syndrome:report of three cases and literature review
HE Ying-dong,L Ji-cheng,CHEN Qian.Postpartum hemolytic uremic syndrome:report of three cases and literature review[J].Chinese Journal of Perinatal Medicine,2010,13(2).
Authors:HE Ying-dong  L Ji-cheng  CHEN Qian
Institution:HE Ying-dong,L(U) Ji-cheng,CHEN Qian
Abstract:Objective To understand the clinical features,differential diagnosis,treatment and prognosis of postpartum hemolytic uremic syndrome (PHUS). Methods Three PHUS cases and relevant literature were reviewed. Results Three patients were admitted because of microangiopathie hemolytic anemia,thrombocytopenia and acute renal failure.which occurred within 3 days after cesarean section.All of them received plasmapheresis and hematodialysis.Now,one of the patients recovered,and the other lives on hematodialysis. Conelusiom Early diagnosis and proper treatment of PHUS ensures a better outcome.
Keywords:Puerperal disorders  Hemolytic-uremic syndrome  Purpura  thromboticthrombocytopenic  Diagnosis
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