血清超敏C反应蛋白和外周血白细胞计数检测对新生儿感染的诊断价值

目的 探讨血清超敏C反应蛋白（hs-CRP）和外周血白细胞（WBC）计数检测对新生儿感染的诊断价值. 方法 选择68例有感染高危因素的足月新生儿（高危组）,另选取同期正常足月新生儿32例为对照组,检测两组血清hs-CRP和WBC. 结果 高危组24 h后检测血清hs-CRP＞3 mg/L为54例（79.4%）高于对照组的8例（25.0%）（χ^2=27.344,P＜0.01）,高危组WBC＞20×10^9/L为21例（30.9%）高于对照组（P＞0.05）;高危组hs-CRP和WBC两项指标检测均异常21例（30.9%）均伴有感染征象,其中9例诊断为新生儿感染. 结论 血清hs-CRP和WBC计数检测有助于新生儿感染的早期判断.

Diagnostic value of high sensitive C-reactive protein(hs-CRP)and count of white blood cell(WBC)in neonatal infection

Objective To investigate the value of the combination of hs-CRP and WBC in infectious high risk infants. Methods 68 infants with infectious high risk factor were divided into high risk group,while 32 normal infants were in control group.Serum hs-CRP level and WBC were measured in the two groups. Results There were 54(79.4%)infants with serum hs-CRP level higher than 3 mg/L in high risk group,while just 8 infants in control group.Significant difference were found between the two groups(x2=27.344,P＜0.01).There were 21(30.9%)infants with WBC higher than 20 × 109/L.No significant difference was found between the two groups(P＞0.05).Serum hs-CRP and WBC were both abnormal in 21 infants with infectious experience,9 infants were diagnosed with neonatal infection. Conclusion Combination measurement of serum hs-CRP level and WBC were useful in early diagnosis of neonatal infection.