Early exposure of dams to a westernized diet has long-term consequences on food intake and physiometabolic homeostasis of the rat offspring |
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| Authors: | Taisy Cinthia Ferro Cavalcante Amanda Alves Marcelino da Silva Maria Cláudia Alheiros Lira Larissa Cavalcanti do Amaral Almeida Ana Patricia Jaques Marques |
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| Affiliation: | 1. Department of Nutrition, Universidade Federal de Pernambuco, UFPERecife-PEBrazil;2. Department of Neuropsychiatry and Behavioral Sciences, UFPERecife-PEBrazil |
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| Abstract: | This study evaluated the long-term effects of a westernized diet during pregnancy and lactation. Female Wistar rats (n?=?12) were divided into two groups according to their food intake, namely, control (C) or westernized (W) diet, throughout pregnancy/lactation. On the 21st day, the male pups were weaned on a standard diet as follows: Control diet (CC) (n?=?8) and westernized diet in perinatal life followed by control diet post weaning (WC) (n?=?8). The levels of fasting (12?h) serum glucose, triglycerides (TG), and total cholesterol and fraction in the pups were determined. During weaning, the WC group showed 14% greater body weight (p?
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| Keywords: | Adulthood food intake glucose and lipid profile rat western-style diet |
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