Obstructive sleep apnea syndrome and chronic kidney disease: a new cardiorenal risk factor |
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| Authors: | Abdullah Ozkok Asiye Kanbay Ali Riza Odabas Adrian Covic |
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| Affiliation: | 1. Division of Nephrology, Department of Internal Medicine;2. Department of Pulmonary Medicine, Istanbul Medeniyet University School of MedicineIstanbulTurkey;3. Nephrology Clinic, Dialysis and Renal Transplant Center, ‘C.I. PARHON’ University Hospital, ‘Gr. T. Popa’ University of Medicine and PharmacyIasiRomania |
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| Abstract: | Clinical and experimental studies revealed that sleep apnea might be an insidious risk factor for the progression of kidney disease and development of cardiovascular events by exacerbating well-known risk factors, namely hypertension, type 2 diabetes mellitus and obesity. Furthermore, sleep apnea also has a negative impact on endothelial function. Therefore, sleep apnea might be defined as a new cardiorenal risk factor. In this review, we aimed to summarize the evidences supporting the complex inter-relations between sleep apnea and development and progression of chronic kidney disease. |
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| Keywords: | Chronic kidney disease hypertension inflammation sleep apnea |
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