The relationship between vitamin D and obesity |
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Authors: | Sanja Soskić Edita Stokić |
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Institution: | 1. Institute of nuclear sciences ‘Vinca’, Laboratory for Radiobiology and Molecular Genetics, University of Belgrade
BelgradeSerbia;2. Clinical Center of Vojvodina, Medical Faculty in Novi Sad
Novi SadSerbia |
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Abstract: | Currently, vitamin D deficiency and obesity are pandemic diseases and they are associated with cardiovascular (CV) disease, metabolic syndrome and type 2 diabetes mellitus (T2DM) and other diseases. Concentrations of 25-hydroxyvitamin D (25(OH)D) (25D) are considered as the best indicator of total body vitamin D stores. An association between reduced circulating 25D concentrations and obesity is well known, but the mechanisms are not totally clear. The role of vitamin D supplementation is still uncertain and prospective interventions will establish its influence, if any, in the treatment of obesity. Vitamin D deficiency is associated with the presence of a cardiometabolic risk profile in the obese. Future trials may establish a role for Vitamin D supplementation in individuals at increased CV risk. |
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Keywords: | Cardiovascular disease Metabolic syndrome Obesity Type 2 diabetes Vitamin D |
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