The effectiveness of oral essential aminoacids and aminoacids containing dialysate in peritoneal dialysis |
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Authors: | Selman Unverdi Ebru Uz Bulent Akgul Mustafa Altay Yasemin Kirac |
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Affiliation: | 1. Department of Nephrology, Ankara Educational and Training HospitalAnkaraTurkey;2. Faculty of Medicine, Department of Nephrology, Yildirim Beyazit UniversityAnkaraTurkey;3. Department of Nephrology, Gaziantep Dr. Ersin Arslan Government HospitalGaziantepTurkey;4. Department of Endocrinology, Kecioren Educational and Training HospitalAnkaraTurkey;5. Department of Nephrology, Koru HospitalAnkaraTurkey |
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Abstract: | Background/Aim: Oral essential amino acids (AAs) containing supplements (EAS) and AA containing dialysate (ACD) are frequently used in peritoneal dialysis (PD) patients with malnutrition. The present study was conducted to investigate two strategies and compare their effects on the malnutrition status of PD patients. Materials and Methods: A total of 31 EAS, 14 ACD patients were enrolled in this study. Serum albumin levels were lower than 3.5?g/dL in all subjects. EAS group patients took five pills containing AAs three times a day with meals. In the other, 2.000?cc of 1.1% ACD was given to patients daily during the study. Demographic and laboratory parameters were analyzed and compared at baseline and 6th month. Results: Significant increases in BMI, albumin, and protein in both groups. Mean albumin levels increased significantly by 0.54?g/dL in ACD group (p?0.005) and 0.49?g/dL in EAS group (p?0.001) following 6 months. Mean albumin and delta albumin levels did not differ between two groups. Conclusion: These strategies may play an important role in increasing albumin levels and improving the nutritional status of PD patients. |
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Keywords: | Albumin amino acid dialysate malnutrition peritoneal dialysis |
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