Successful use of rituximab in fibrillary glomerulopathy |
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Authors: | Asad Chaudhary Nich L Cossey Patrick D Walker Barry M Wall |
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Institution: | 1. Department of Nephrology, University of Tennessee Health Science Center
Memphis, TNUSA;2. Nephropathology Associates
Little Rock, ARUSA;3. Department of Nephrology at Veterans Affairs Medical Center
Memphis, TNUSA |
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Abstract: | Fibrillary glomerulopathy (FG) can occur either alone or co-existing with other proteinuric glomerular disorders. FG has been associated with poor renal outcomes leading to End Stage Renal Disease (ESRD). Since FG is a relatively rare disorder, limited information is available concerning treatment protocols. We present two patients with FG who were treated with rituximab after they had already progressed to stage 3 chronic kidney disease (CKD) with worsening proteinuria. Rituximab therapy resulted in long-term stabilization of renal function. |
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Keywords: | Chronic kidney disease fibrillary glomerulonephritis rituximab treatment |
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