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Enhancement of EEG lateralizing signs in temporal lobe epilepsy: a trial of diazepam.
Authors:M A Brazier  P H Crandall  G O Walsh
Affiliation:1. Department of Anatomy, Division of Neurosurgery, University of California Medical Center, Los Angeles, California, USA;2. Department of Neurology, University of California Medical Center, Los Angeles, California, USA
Abstract:Reports are given of a subgroup of 13 patients with intractable seizures in whom unequivocal lateralizing signs were extremely difficult to obtain. On the basis that normal cerebral neurons react to intravenous diazepam by giving fast activity in the EEG, this simple test was given interictally in an attempt to differentiate, by computer analysis, normal and abnormal responses in the EEG. The results are reported for each patient in comparison with all other available lateralizing signs, clinical and electroencephalographic from scalp and deeply implanted electrodes, both ictally and interictally.
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