| 原发性中枢神经系统淋巴瘤临床和病理分析 |
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| 引用本文： | 吴康智,杨建民,宋献民,许小平,侯军,王健民. 原发性中枢神经系统淋巴瘤临床和病理分析[J]. 第二军医大学学报, 2004, 25(6): 687-688 |
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| 作者姓名： | 吴康智 杨建民 宋献民 许小平 侯军 王健民 |
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| 作者单位： | 第二军医大学长海医院血液科,上海,200433;武警青海总队医院内一科,西宁,810000;第二军医大学长海医院血液科,上海,200433 |
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| 摘 要： | 目的:分析原发性中枢神经系统淋巴瘤的临床和病理特征.方法:对9例原发性中枢性神经系统恶性淋巴瘤(PCNSL)患者(男5例,女4例,年龄39～70岁,平均54.6岁)的临床、影像学与病理学特征进行分析.结果:PCNSL临床表现复杂,颅内高压为主要临床表现之一,头颅CT以及MRI检查显示中枢侵及额叶多见.PCNSL主要起源于B细胞,综合治疗效果好,中位生存期为15个月.结论:PCNSL临床与影像学缺乏特异性表现,脑活组织病理学检查是确诊本病的主要手段,活检确诊后积极放化疗可取得较好的效果.
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| 关 键 词： | 原发性中枢神经系统淋巴瘤 活组织检查 脑 |
| 文章编号： | 0258-879(2004)06-0687-02 |
| 修稿时间： | 2003-10-08 |
Clinical and pathological features of primary central nervous system lymphoma |
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| WU Kang-Zhi ,,YANG Jian-Min ,SONG Xian-Min ,XU Xiao-Ping ,HOU Jun ,WANG Jian-Min. Clinical and pathological features of primary central nervous system lymphoma[J]. Former Academic Journal of Second Military Medical University, 2004, 25(6): 687-688 |
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| Authors: | WU Kang-Zhi YANG Jian-Min SONG Xian-Min XU Xiao-Ping HOU Jun WANG Jian-Min |
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| Affiliation: | WU Kang-Zhi 1,2,YANG Jian-Min 1,SONG Xian-Min 1,XU Xiao-Ping 1,HOU Jun 1,WANG Jian-Min 1 |
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| Abstract: | Objective:To study the clinical,radiological and pathological features of primary central nervous system lym-phoma(PCNSL).Methods:The clinical,laboratory,neuroradiological and pathological data of9patients with PCNSL were analyzed retrospectively.Results:Increased intracranial pressure was the main clinical findings of PCNSL.CT and MRI showed solitary or multiple intracranical masses in the frontal lobe.PCNSL was mostly of B-cell origin.The outcome of com-prehensive treatment was favorable.Conclusion:PCNSL patients usually do not show characteristic clinical manifestation or findings in imaging scanning.Brain biopsy and pathological examination might be more reliable than others.Comprehensive treatment including radiotherapy and chemotherapy can achieve good effects.[ |
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| Keywords: | primary central nervous system lymphoma biopsy brain |
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