糖尿病合并脑血管病急性期中医证候演变规律研究

目的探讨糖尿病合并脑血管病急性期中医证候演变规律。方法选择糖尿病合并脑血管病患者137例,非糖尿病合并脑血管患者158例作为研究对象,中医证候要素分为风、火、痰、瘀、气虚、阴虚阳亢,分别于入院时、发病第7天、14天、28天,4个时点进行证候采集和评价,进行两组比较。结果糖尿病合并脑血管病组证候演变规律为阴虚风动证→痰火证→痰瘀证→气虚血瘀证。非糖尿病合并脑血管病组证候演变规律为风痰证→痰火证→痰瘀证→痰瘀证。结论糖尿病合并脑血管病组与非糖尿病合并脑血管病组存在不同的证候演变规律,为中风不同时期的中医临床辨证施治提供了理论依据。

Evolution laws of TCM syndromes of diabetes complicating cerebrovascular disease at acute stage

Objective To discuss the evolution laws of TCM syndromes of diabetes complicating cerebrovascular disease at acute stage.Methods The patients with diabetes complicating cerebrovascular disease(n=137,complicating group) and those without diabetes complicating cerebrovascular disease(n=158,other disease group) were selected.The TCM syndrome factors included wind,fire,phlegm,blood stasis,qi deficiency and yin deficiency with yang hyperactivity,and they were collected,reviewed and compared at four time points(hospitalized day,7th day,14th day and 28th day).Results The evolution laws of TCM syndromes in complicating group were from syndrome of wind stirring due to yin deficiency to phlegm-fire syndrome to phlegm-stasis syndrome to qi deficiency and blood stasis syndrome,and that in other disease group,from wind-phlegm syndrome to phlegm-fire syndrome to phlegm-stasis syndrome to phlegm-stasis syndrome.Conclusion The different evolution laws in diabetes complicating cerebrovascular disease and other diseases provide theoretical basis for treating stroke with TCM at different stages.